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氟西汀 盐酸盐 5-HT再摄取抑制剂 ≥98%(HPLC)
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价格
¥30.00
货号
F131623-1g
市场价
¥0.00
品牌
阿拉丁
销量
0
库存量
100
CAS号
56296-78-7
分子式
C17H18F3NO·HCl
分子量
345.79

基本信息

产品名称氟西汀 盐酸盐
英文名称Fluoxetine HCl
别名氟苯氧丙胺 盐酸盐;140 盐酸盐;(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯丙胺 盐酸盐;氟西汀 HCl;N-甲基-3-苯基-3-[4-(三氟甲基)苯氧基]丙胺盐酸盐
英文别名Fluoxetine hydrochloride;N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride
规格或纯度≥98%(HPLC)
运输条件冰袋运输
生化机理Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT.Potent, selective 5-HT reuptake inhibitor. Antidepressant in vivo . Binds to rat and human 5-HT transporters with K i values of 2 and 0.9-20 nM, respectively. Shows around 150-900-fold selectivity over 5-HT 1A , 5-HT 2A , H 1 , α 1 , α 2 -adrenergic and m

一般描述

Fluoxetine HCl是一种抗抑郁剂,选择性抑制5-羟色胺再摄取。An ST (SERT) inhibitor.


Fluoxetine is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
An ST (SERT) inhibitor.


application:

Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor. It is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder and premenstrual dysphoric disorder (PMDD).


product description:

Fluoxetine hydrochloride is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs).

安全信息

标识符号 GHS09, GHS05, GHS07
信号词Danger
警示性声明P305+P351+P338,P273,P280
危害声明H302,H318,H400
个人防护设备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
WGK3

相关属性

CAS编号56296-78-7
熔点159 °C
溶解性Soluble in water (4 mg/mL), DMSO (>5 mg/mL), acetone, acetonitrile, chloroform, and methanol.
储存温度2-8°C储存
Reaxys-RN6759273
RTECSUI4050000
MDL号MFCD00214288
分子量345.79
分子式C17H18F3NO·HCl
EC号260-101-2
品牌阿拉丁
备注如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。
PubChem CID62857


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