| 产品名称 | 氟西汀 盐酸盐 |
|---|---|
| 英文名称 | Fluoxetine HCl |
| 别名 | 氟苯氧丙胺 盐酸盐;140 盐酸盐;(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯丙胺 盐酸盐;氟西汀 HCl;N-甲基-3-苯基-3-[4-(三氟甲基)苯氧基]丙胺盐酸盐 |
| 英文别名 | Fluoxetine hydrochloride;N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride |
| 规格或纯度 | ≥98%(HPLC) |
| 运输条件 | 冰袋运输 |
| 生化机理 | Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT.Potent, selective 5-HT reuptake inhibitor. Antidepressant in vivo . Binds to rat and human 5-HT transporters with K i values of 2 and 0.9-20 nM, respectively. Shows around 150-900-fold selectivity over 5-HT 1A , 5-HT 2A , H 1 , α 1 , α 2 -adrenergic and m |
Fluoxetine HCl是一种抗抑郁剂,选择性抑制5-羟色胺再摄取。An ST (SERT) inhibitor.
Fluoxetine is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
An ST (SERT) inhibitor.
application:
Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor. It is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder and premenstrual dysphoric disorder (PMDD).
product description:
Fluoxetine hydrochloride is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs).
| 标识符号 | GHS09, GHS05, GHS07 |
|---|---|
| 信号词 | Danger |
| 警示性声明 | P305+P351+P338,P273,P280 |
| 危害声明 | H302,H318,H400 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| WGK | 3 |
| CAS编号 | 56296-78-7 |
|---|---|
| 熔点 | 159 °C |
| 溶解性 | Soluble in water (4 mg/mL), DMSO (>5 mg/mL), acetone, acetonitrile, chloroform, and methanol. |
| 储存温度 | 2-8°C储存 |
| Reaxys-RN | 6759273 |
| RTECS | UI4050000 |
| MDL号 | MFCD00214288 |
| 分子量 | 345.79 |
| 分子式 | C17H18F3NO·HCl |
| EC号 | 260-101-2 |
| 品牌 | 阿拉丁 |
| 备注 | 如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
| PubChem CID | 62857 |