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基本信息
| 产品名称 | 3,4-苯并芘标准溶液 |
|---|---|
| 英文名称 | 3,4-Benzopyrene solution |
| 别名 | 3,4-苯并芘 |
| 英文别名 | 3,4-Benzpyrene Benzo[def]chrysene Benzo[a]pyrene |
| 应用 | A polycyclic aromatic hydrocarbon (PAH), environmental pollutant and carcinogen. Used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR. |
| 规格或纯度 | analytical standard,5.0ug/mL in methanol |
一般描述
A polycyclic aromatic hydrocarbon (PAH), environmental pollutant and carcinogen. Used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
A polycyclic aromatic hydrocarbon (PAH), environmental pollutant and carcinogen. Used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
安全信息
| 标识符号 | GHS07, GHS08, GHS09 |
|---|---|
| 信号词 | Danger |
| 警示性声明 | P201,P273,P280,P308+P313,P501 |
| 危害声明 | H317,H340,H350,H360,H410 |
| WGK | 3 |
| Merck Index | 1103 |
相关属性
| CAS编号 | 50-32-8 |
|---|---|
| 敏感性 | 对光线敏感 |
| 溶解性 | 不溶于水，微溶于乙醇、甲醇，溶于苯、甲苯、二甲苯、氯仿、乙醚、丙酮等。 |
| 储存温度 | 阴凉干燥通风处存储。 |
| RTECS | DJ3675000 |
| MDL号 | MFCD00003602 |
| 密度 | 1.0000 |
| 分子量 | 252.31 |
| 分子式 | C20H12 |
| EC号 | 200-028-5 |
| 品牌 | 阿拉丁 |
| PubChem CID | 2336 |