产品名称 | 5-乙炔基-2'-脱氧尿苷(EdU) |
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英文名称 | 5-Ethynyl-2'-deoxyuridine(EdU) |
别名 | 5-乙炔基-2‘-去氧尿苷 |
英文别名 | 5-EdU;2'-Deoxy-5-ethynyluridine;EdU;5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione |
规格或纯度 | ≥98% |
运输条件 | 超低温冰袋运输 |
产品介绍:
5-乙炔基-2′-脱氧尿苷(EdU)是一种胸苷类似物,可掺入到新合成的复制DNA中,以检测细胞增殖。它具有炔烃连接基团,可通过高效的点击化学反应与含叠氮基的荧光探针连接。EdU核苷可以掺入到培养物或动物的细胞DNA中,并且无明显的毒性。该测定是比抗BrdU测定更简单的细胞增殖测定方法。
5-Ethynyl-2'-deoxyuridine(EdU) is an extensively used nucleoside analog used as a probe for DNA synthesis. 5-Ethynyl-2’-deoxyuridine is known as an toxic anti-metabolite, which potentially causes DNA instabiliy, necrosis and cell-cycle arrest, therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.
An extensively used nucleoside analog
标识符号 | GHS08 |
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信号词 | Danger |
警示性声明 | P201,P308+P313,P281 |
危害声明 | H340,H361 |
WGK | 3 |
CAS编号 | 61135-33-9 |
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敏感性 | 对热及光敏感 |
比旋光度 | [α]D:23° (C=0.7,MeOH) |
熔点 | 199 °C |
溶解性 | Soluble in methanol, DMSO, water (slightly), DMF, and chloroform |
储存温度 | 避光,-20°C储存 |
MDL号 | MFCD01675687 |
分子量 | 252.22 |
分子式 | C11H12N2O5 |
品牌 | 阿拉丁 |
PubChem CID | 472172 |