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基本信息
| 产品名称 | 尿苷-5′-二磷酸-N-乙酰基-葡糖胺钠盐 |
|---|---|
| 英文名称 | Uridine 5’-Diphospho-N-acetylglucosamine Disodium Salt |
| 别名 | 尿苷 5'-(三氢二磷酸酯) P'-[2-(乙酰氨基)-2-脱氧-alpha-D-吡喃葡萄糖基]酯钠盐(1:2)；5′-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐;UDP-GlcNAc；UDPAG；UDP-N-乙酰葡糖胺； |
| 英文别名 | UDP-N-acetylglucosamine;UDP-GlcNAc;UDPAG;Uridine 5'-(Trihydrogendiphosphate) P'-[2-(Acetylamino)-2-Deoxy-alpha-D-Glucopyranosyl] Ester Sodium Salt (1:2)；UDP-GlcNAc Disodium Salt；UDP-α-D-N-Acetylglucosamine Disodium Salt |
| 应用 | Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used: · as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay · as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC) · in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate |
| 规格或纯度 | ≥98% |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | 供体底物可用于在合成N-聚糖中将GlcNAc转移至多萜醇前体。 UDP-GlcNAc还在O-GlcNAc信号转导中通过O-GlcNAc转移酶（OGT）作为与丝氨酸/苏氨酸残基连接的GlcNAc的来源。N聚糖合成中将GlcNAc转移至二元醇前体的供体底物。在O-GlcNAc信号转导中，还用作通过O-GlcNAc转移酶（OGT）连接到丝氨酸/苏氨酸残基的GlcNAc的来源。 |
一般描述
Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sμgar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sμgar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used: · as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay · as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC) · in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate
Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sugar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.
安全信息
| 标识符号 | GHS07 |
|---|---|
| 信号词 | Warning |
| 警示性声明 | P261,P305+P351+P338,P280,P302+P352,P312,P304+P340,P337+P313,P362+P364,P332+P313 |
| 危害声明 | H315,H319,H335 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
| WGK | 3 |
相关属性
| CAS编号 | 91183-98-1 |
|---|---|
| 溶解性 | DMSO: 10mM( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
| 储存温度 | -20°C储存 |
| MDL号 | MFCD00799985 |
| 分子量 | 651.32 |
| 分子式 | C17H25N3O17P2Na2 |
| EC号 | 293-820-5 |
| 品牌 | 阿拉丁 |
| 备注 | 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| PubChem CID | 133612027 |