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基本信息
| 产品名称 | 棉子酚 |
|---|---|
| 英文名称 | (±)-Gossypol from cotton seeds |
| 别名 | 棉酚；AT101；(±)-2,2′-双（8-甲酰基-1,6,7-三羟基-5-异丙基-3-甲基萘）；（±）-棉酚；棉籽酚；棉子醇 |
| 英文别名 | 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde;(±)-Gossypol；1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl-2,2'-binaphthyl-8,8'-dialdehyde;2,2'-Bis[1,6,7-trihydroxy-3-methyl-5-isopropy |
| 规格或纯度 | ≥95% |
| 运输条件 | 冰袋运输 |
| 生化机理 | Gossypol is a male antifertility agent and PAF antagonist/inhibitor. Gossypol is a poisonous pigment found in cottonseed and its name is derived from the botanical name of the cotton plant, Gossypium.. Gossypium is extracted from selected hybrid species between two Gossypium species, Gossypium hirsutum and Gossypium barbadens. As a PAF antagonist/inhibitor, Gossypium markedly inhibited the contractile responses of guinea pig lung parenchyma strips stimulated with leukotriene B4, seukotriene D4, and PAF-acether. .Proapoptotic agent derived from cottonseed. Exhibits a wide range of biological effects including anticancer and antifertility activity. Downregulates Bcl-2, p53 and various enzymes including caspases and dehydrogenases. |
一般描述
Product Description：
Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain anitumor, anitviral, and antioxidant properties. Gossypol is a reversible inhibitor of PP2B (protein phosphatase 2B), mitotic kinesin Eg5, and PKC (protein kinase C). Gossypol also potentially inhibits PAF-R, Bcl-2, 5-LO (5-lipoxygenase), 12-LO, and leukotriene-induced guinea pig parenchyma contractions. Gossypol is an inhibitor of Bcl-xl, PKD and p107.
An inhibitor of PKC, Bcl-2, 5-LO, and 12-LO.
Product Application：
Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.
Product Description：
Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain anitumor, anitviral, and antioxidant properties. Gossypol is a reversible inhibitor of PP2B (protein phosphatase 2B), mitotic kinesin Eg5, and PKC (protein kinase C). Gossypol also potentially inhibits PAF-R, Bcl-2, 5-LO (5-lipoxygenase), 12-LO, and leukotriene-induced guinea pig parenchyma contractions. Gossypol is an inhibitor of Bcl-xl, PKD and p107.
An inhibitor of PKC, Bcl-2, 5-LO, and 12-LO.
Product Application：
Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.
安全信息
相关属性
| CAS编号 | 303-45-7 | |
|---|---|---|
| 敏感性 | 对光敏感 | |
| 溶解性 | Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. | |
| 储存温度 | 2-8°C储存,避光 | |
| RTECS | DU3100000 | |
| 分子量 | 518.55 | |
| 分子式 | C30H30O8 | |
| 品牌 | 阿拉丁 | |
| 备注 | 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 | |
| PubChem CID | 3503 |