易挥发。易吸湿。于230℃以上分解为三甲胺和氯甲烷。易溶于甲醇，溶于水和热乙醇，不溶于乙醚和氯仿。有毒，半数致死量(小鼠，腹腔)25mg/kg。有刺激性。 Tetramethylammonium chloride (TMAC) is structurally similar to alkyltrimethylammonium salts. Oxidation of TMAC yields formaldehyde and trimethlamine. It is considered as poor phase-transfer catalyst for most reactions as it is insoluble in organic media. However, it is highly suitable as phase-transfer catalyst for fluorination of chlorobenzaldehydes along with alkali metal fluorides which yield 1,2,2,2-tetrafluoroethyldifluoromethyl ether.极谱分析试剂。
Tetramethylammonium chloride (TMAC) is structurally similar to alkyltrimethylammonium salts. Oxidation of TMAC yields formaldehyde and trimethlamine. It is considered as poor phase-transfer catalyst for most reactions as it is insoluble in organic media. However, it is highly suitable as phase-transfer catalyst for fluorination of chlorobenzaldehydes along with alkali metal fluorides which yield 1,2,2,2-tetrafluoroethyldifluoromethyl ether.
Tetramethylammonium chloride along with N-hydroxyphthalimide and xanthone may be used as an efficient chloride catalytic system for the aerobic oxidation of hydrocarbons to form the corresponding oxygenated compounds. It may also be used as a phase transfer catalyst for the synthesis of aryl fluorides via selective chloride/fluoride exchange reaction of activated aryl chlorides with potassium fluoride in solid-liquid phase.