63.00
5-氟靛红 >98.0%(HPLC)
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价格
63.00
货号
F138845-5g
市场价
0.00
品牌
阿拉丁
销量
0
库存量
100
CAS号
443-69-6
分子式
C8H4FNO2
分子量
165.12

基本信息

产品名称5-氟靛红
英文名称5-Fluoroisatin
别名5-氟吲哚醌;5-氟二氢吲哚-2,3-二酮;5-氟-2,3-吲哚啉二酮
英文别名5-Fluoroindole-2,3-dione;5-Fluoro-2,3-indolinedione; NSC 39161
规格或纯度>98.0%(HPLC)
运输条件常规运输

一般描述

5-Fluoroisatin has been reported as the precursor of the Sunitinib (Sutent) drug. 5-Fluoroisatin has been approved by the Food and Drugs Administration (FDA) in 2006 for the treatment of renal cell carcinoma (RCC) and gastrointestinal stromal tumor (GIST).
5-Fluoroisatin may be used as reaction-based probe for live-cell detection of peroxynitrite by 19F magnetic resonance spectroscopy;in non-invasive detection of peroxynitrite (ONOO(-)) formation in living lung epithelial cells stimulated with interferon-γ (IFN-γ);in the synthesis of bis-Schiff bases, via condensation with aromatic primary bis-amines in water suspension medium without using any organic solvent or acid catalyst;in the synthesis of 3-acetonyl-5-fluoro-3-hydroxyoxindole Reactant for preparation of:Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds;Potential antimycobacterial agents;Inhibitors of c-Met kinase;Inhibitors of TAK1 kinase;Herpes simplex virus inhibitors;IKKβ inhibitors; Inhibitors of vitiligo disease; Potential drug candidates with anti-HIV activity and anti-tubercular activity


5-Fluoroisatin has been reported as the precursor of the Sunitinib (Sutent) drug. 5-Fluoroisatin has been approved by the Food and Drugs Administration (FDA) in 2006 for the treatment of renal cell carcinoma (RCC) and gastrointestinal stromal tumor (GIST).
5-Fluoroisatin may be used as reaction-based probe for live-cell detection of peroxynitrite by 19F magnetic resonance spectroscopy;in non-invasive detection of peroxynitrite (ONOO(-)) formation in living lung epithelial cells stimulated with interferon-γ (IFN-γ);in the synthesis of bis-Schiff bases, via condensation with aromatic primary bis-amines in water suspension medium without using any organic solvent or acid catalyst;in the synthesis of 3-acetonyl-5-fluoro-3-hydroxyoxindole Reactant for preparation of:Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds;Potential antimycobacterial agents;Inhibitors of c-Met kinase;Inhibitors of TAK1 kinase;Herpes simplex virus inhibitors;IKKβ inhibitors; Inhibitors of vitiligo disease; Potential drug candidates with anti-HIV activity and anti-tubercular activity

安全信息

标识符号 GHS07
信号词Warning
警示性声明P305+P351+P338,P280,P302+P352,P264,P337+P313,P362+P364,P332+P313
危害声明H315,H319
个人防护设备dust mask type N95 (US), Eyeshields, Gloves
WGK3

相关属性

CAS编号443-69-6
熔点224-230°C
Reaxys-RN131241
MDL号MFCD00022795
分子量165.12
分子式C8H4FNO2
品牌阿拉丁
PubChem CID236566


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