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A redox buffer that increases the folding rate of disulfide-containing proteins relative to traditional buffers such as glutathione and glutathione-disulfide. Also a useful synthetic intermediate for the preparation of novel anti inflammatory agents.A redox buffer that increases the folding rate of disulfide-containing proteins

A redox buffer that increases the folding rate of disulfide-containing proteins relative to traditional buffers such as glutathione and glutathione-disulfide. Also a useful synthetic intermediate for the preparation of novel anti inflammatory agents.
A redox buffer that increases the folding rate of disulfide-containing proteins

application：

4-Mercaptophenylacetic acid has been used in the preparation of small ubiquitin-like modifier peptides from bis(2-sulfanylethyl)amido peptide via sequential native chemical ligation.

It can be used:On-resin preparation of peptide-α thiophenylesters which are used in a chemical ligation process for the chemical synthesis of peptides.In one pot deprotection of (acetamido-methyl)cysteine following native chemical ligation and/or desulfurization method for the preparation of peptides.Palladium facilitated deprotection of N-terminal cysteine through native chemical ligation method for the preparation of synthetically challenging proteins.