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基本信息
| 产品名称 | 腺嘌呤 |
|---|---|
| 英文名称 | Adenine |
| 别名 | 6-氨基嘌呤;维生素 B4 |
| 英文别名 | 6-Aminopurine;Vitamin B4 |
| 应用 | A purine nucleobase and a component of DNA |
| 规格或纯度 | 98% |
| 运输条件 | 常规运输 |
| 生化机理 | Adenine is essential for many in vivo and in vitro biochemical processes. Adenine is converted to adenosine with ribose. On phosphorylation, it forms AMP, ADP and ATP. ATP is the energy currency of the cell and is required during cellular metabolism. Adenine is metabolized to is 2,8-dihydroxyadenine, which on accumulation in proximal tubules leads to the induction of chronic kidney disease (CKD) with severe anemia in rats. Adenine based derivatives elicit antiviral functionality against dsDNA viruses and are exploited for generating antiviral scaffolds. |
一般描述
Adenine, Cell Culture is synthetic and therefore free of any contamination with related natural products.A purine nucleobase and a component of DNA
Adenine is a purine nucleobase. It is part of DNA, and RNA. Adenine is also a component of cofactors (NAD, FAD) and signaling molecules (cAMP).
Adenine is suitable for use:as a component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boronas a food supplement for adult rats to investigate the effects of dietary adenine overloadas a nucleic acid base supplement in the basal media used to grow anaerobic Bacillus mojavensis and Bacillus subtilis in a study to show that DNA or deoxyribonucleosides are required for the anaerobic growth of these bacteriaas an additive to investigate the effects of adenine on CH4 production and on fermentation by ruminal batch cultures from nonlactating Holstein cowsas a part of adenine diet in rats in a study to identify blood markers for early stages of adenine-induced chronic kidney disease (CKD)
安全信息
相关属性
| CAS编号 | 73-24-5 |
|---|---|
| 敏感性 | 对湿度敏感 |
| 熔点 | >360°C |
| 溶解性 | Soluble in water (0.5 g/L) at 20 °C, hot NH4OH, DMSO, alkali, acid, and hot water. Insoluble in chloroform, and ether. |
| 储存温度 | 室温 |
| Reaxys-RN | 608603 |
| RTECS | AU6125000 |
| MDL号 | MFCD00041790 |
| 密度 | 1.612 |
| 分子量 | 135.13 |
| 分子式 | C5H5N5 |
| EC号 | 200-796-1 |
| 品牌 | 阿拉丁 |
| 备注 | 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| Smiles | N.N.OS(=O)(=O)OOS(=O)(=O)O;NC1=NC=NC2=NC=NC12;Nc1nc[nH]c2ncnc12;Nc1ncnc2[nH]cnc12;Nc1ncnc2nc[nH]c12 |
| PubChem CID | 190 |