| 产品名称 | Veliparib |
|---|---|
| 英文名称 | Veliparib |
| 别名 | ABT-888;PARP抑制剂 |
| 英文别名 | ABT-888; 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide |
| 应用 | A potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents |
| 规格或纯度 | ≥99% |
| 运输条件 | 冰袋运输 |
| 生化机理 | Veliparib is a potent inhibitor of both PARP-1 and PARP-2 by [3H]NAD+ with Kis of 5.2 and 2.9 nmol/L, respectively. |
Veliparib is a potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition.A potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents
Veliparib is a potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition.
A potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents
| CAS编号 | 912444-00-9 |
|---|---|
| 溶解性 | DMSO ≥45mg/mL Water <1.2mg/mL Ethanol <1.2.mg/mL |
| 储存温度 | 2-8°C |
| 分子量 | 244.3 |
| 分子式 | C13H16N4O |
| 品牌 | 阿拉丁 |
| PubChem CID | 11960529 |