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基本信息
| 产品名称 | 奎诺二甲基丙烯酸酯 |
|---|---|
| 英文名称 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
| 别名 | 水溶性维生素E;6-羟基-2,5,7,8-四甲基苯并二氢吡喃-2-甲酸,(±)-6-羟基-2,5,7,8-四甲基色满-2-羧酸 |
| 英文别名 | Trolox;6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid |
| 规格或纯度 | 98% |
| 运输条件 | 冰袋运输 |
| 生化机理 | 抗氧化剂维生素E衍生物。表现出脂质过氧化，DPPH°清除和HO°清除活性。经常用作抗氧化剂标准。具有细胞渗透性和水溶性。 |
一般描述
Trolox is an antioxidant derived from water-soluble vitamin E, with oxygen quenching activity. The activity of Trolox ranges between ferulic acid and p-coumaric acid. Studies show that lipid peroxidation, cytotoxicity, and apoptosis induced by cytochrome P450 2E1 in Hep G2 cells is blocked in the presence of Trolox. It has been observed that Trolox can quench free radicals and inhibit methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. In addition, Trolox has demonstrated the ability to reduce cytotoxicity of Microcystis aerμginosa and microcystin-LR in Artemia franciscana nauplii. ()-6-hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid (Trolox) exhibits free radical scavenging and antioxidant activities.
An antioxidant derived from water-soluble vitamin E ()-6- hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid (Trolox) has been used in the equivalent antioxidant test (TEAC) of 6-hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid to determine different fruits.
Trolox is an antioxidant derived from water-soluble vitamin E, with oxygen quenching activity. The activity of Trolox ranges between ferulic acid and p-coumaric acid. Studies show that lipid peroxidation, cytotoxicity, and apoptosis induced by cytochrome P450 2E1 in Hep G2 cells is blocked in the presence of Trolox. It has been observed that Trolox can quench free radicals and inhibit methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. In addition, Trolox has demonstrated the ability to reduce cytotoxicity of Microcystis aeruginosa and microcystin-LR in Artemia franciscana nauplii.
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.
An antioxidant derived from water-soluble vitamin E
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) has been used in 6-hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to determine the total antioxidant capacity of different fruit species.
安全信息
| 标识符号 | GHS07 |
|---|---|
| 信号词 | Warning |
| 警示性声明 | P305+P351+P338,P501,P264,P270 |
| 危害声明 | H315,H319,H335 |
| 个人防护设备 | dust mask type N95 (US)， Eyeshields， Gloves |
| WGK | 2 |
相关属性
| CAS编号 | 53188-07-1 |
|---|---|
| 敏感性 | 空气敏感 |
| 熔点 | 187-189 °C |
| 溶解性 | Soluble in 100% ethanol (25 mg/ml), methanol, water(slightly 0.5mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml) |
| 储存温度 | 2-8°C储存,充氩 |
| Reaxys-RN | 5052542 |
| RTECS | DJ2273000 |
| MDL号 | MFCD00006846 |
| 分子量 | 250.29 |
| 分子式 | C14H18O4 |
| 品牌 | 阿拉丁 |
| 备注 | 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| PubChem CID | 40634 |