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二硫化四乙基秋兰姆 97%
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价格
¥36.00
货号
T110101-25g
市场价
¥0.00
品牌
阿拉丁
销量
0
库存量
100
CAS号
97-77-8
分子式
C10H20N2S4
分子量
296.54

基本信息

产品名称二硫化四乙基秋兰姆
英文名称Tetraethylthiuram disulfide
别名双硫伦;TETD;Disulfiram
英文别名Disulfiram; Bis(diethylthiocarbamyl) disulfide; Bis(diethylthiocarbamoyl) disulfide; TETD
应用醇脱氢酶抑制剂。
An ALDH and tumor cell growth inhibitor
规格或纯度97%
运输条件常规运输

一般描述

Disulfiram is a DNA demethylating agent and DIG1 inducer which inhibits prostate cancer cell growth by inhibition of DNA methyltransferase (Dnmt). In addition, studies indicate that disulfiram inhibits aldehyde dehydrogenase (ALDH) resulting in the accumulation of acetaldehyde upon ethanol ingestion. Alternate studies show that disulfiram also inhibits dopamine β-hydroxylase (DBH), an enzyme important in converting dopamine to norepinephrine in noradrenergic neurons. Futhermore, disulfiram can reduce toxicity and carcinogenesis by inhibiting the cytochrome P450IIE1 (CYP2E1). It has been reported that disulfiram can also inhibit tumor cell growth via binding to cellular copper, which inhibits proteosome activity and induces apoptosis. Disulfiram is an inhibitor of ADH and V-ATPase醇脱氢酶抑制剂。 An ALDH and tumor cell growth inhibitor


Disulfiram is a DNA demethylating agent and DIG1 inducer which inhibits prostate cancer cell growth by inhibition of DNA methyltransferase (Dnmt). In addition, studies indicate that disulfiram inhibits aldehyde dehydrogenase (ALDH) resulting in the accumulation of acetaldehyde upon ethanol ingestion. Alternate studies show that disulfiram also inhibits dopamine β-hydroxylase (DBH), an enzyme important in converting dopamine to norepinephrine in noradrenergic neurons. Futhermore, disulfiram can reduce toxicity and carcinogenesis by inhibiting the cytochrome P450IIE1 (CYP2E1). It has been reported that disulfiram can also inhibit tumor cell growth via binding to cellular copper, which inhibits proteosome activity and induces apoptosis. Disulfiram is an inhibitor of ADH and V-ATPase
An ALDH and tumor cell growth inhibitor

安全信息

标识符号GHS08 GHS08, GHS09 GHS09, GHS07 GHS07
警示性声明P273,P280,P501
危害声明H373,H302,H317,H410
个人防护设备dust mask type N95 (US),Eyeshields,Faceshields,Gloves
WGK3
Merck Index3364
UN Number3077

相关属性

CAS编号97-77-8
熔点69-71°C
溶解性Soluble in water (4 mg/l at 25 °C), acohol (38.2 mg/ml), ether (71.4 mg/ml), chloroform, and acetonitrile
Reaxys-RN1712560
RTECSJO1225000
MDL号MFCD00009048
密度1.27
分子量296.54
分子式C10H20N2S4
EC号202-607-8
品牌阿拉丁
备注250g卖完停产,不再备货
PubChem CID3117


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