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熊果酸 93%
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价格
￥58.00
货号
U107243-250mg
市场价
￥0.00
品牌
阿拉丁
销量
0
库存量
100
CAS号
77-52-1
分子式
C30H48O3
分子量
456.7
基本信息
| 产品名称 | 熊果酸 |
|---|---|
| 英文名称 | Ursolic acid |
| 别名 | 乌苏酸;乌索酸 |
| 英文别名 | 3β-Hydroxy-12-ursen-28-ic acid |
| 应用 | An anti-angiogenic and anti-proliferative agent |
| 规格或纯度 | 93% |
| 运输条件 | 冰袋运输 |
| 生化机理 | Ursolic Acid, a naturally occurring triterpenoid, has been noted to demonstrate anti-angiogenic and anti-proliferative properties. Mechanistic studies sμggest that this compound down-regulates MMP-2 and uPA expression in cells via inhibition of Akt, JNK, mammalian target of Rapamycin phosphorylation, and levels of NFκB protein in the nucleus. Other experiments have shown that Ursolic Acid may improve blood glucose, glucose tolerance, insulin tolerance, glycosylated hemoglobin, and plasma leptin levels in diabetic murine models. Additionally, this agent displays a capacity to induce cell cycle arrest and apoptosis throμgh activation of p53 pathway and Bax protein, as well as down-regulation of Bcl-2. |
一般描述
存在于天然植物中的一种三萜类化合物。不溶于水，溶于2%酒精的NaOH，溶于热冰醋酸，中度溶于丙酮，微溶于醇、醚、氯仿和二硫化碳。 An anti-angiogenic and anti-proliferative agent
An anti-angiogenic and anti-proliferative agent
安全信息
| 个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
|---|---|
| Merck Index | 9890 |
相关属性
| CAS编号 | 77-52-1 |
|---|---|
| 比旋光度 | 61° (C=1,Pyridine) |
| 熔点 | 283-285°C |
| 溶解性 | Soluble in ethanol (5 mg/ml warm), DMSO (>25 mg/ml warm), and DMF. Insoluble in water. |
| 储存温度 | 2-8°C储存 |
| MDL号 | MFCD00009621 |
| 密度 | 1.09 |
| 分子量 | 456.7 |
| 分子式 | C30H48O3 |
| EC号 | 201-034-0 |
| 品牌 | 阿拉丁 |
| Smiles | C[C@@H]1CC[C@]2(CC[C@@]3(C)C(=CC[C@H]4[C@]5(C)CC[C@H](O)C(C)(C)[C@H]5CC[C@]34C)[C@H]2[C@H]1C)C(=O)O;C[C@@H]1CC[C@]2(CC[C@@]3(C)C(=CC[C@H]4[C@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]34C)[C@H]2[C@H]1C)C(=O)O;C[C@@H]1CC[C@]2(CC[C@@]3(C)C(=CCC4[C@]5(C)CC[C@H](O)C(C)(C) |
| PubChem CID | 64945 |